Protein kinase C, an elusive therapeutic target?
نویسندگان
چکیده
منابع مشابه
Protein kinase C as a therapeutic target.
The recognition of protein kinase C (PKC) as the long soughtafter receptor for the tumor-promoting phorbol esters established the potential role of PKC in carcinogenesis and as a potentially important target for cancer therapeutics (1, 2). PKC is a family of serine/threonine kinases that regulate a variety of cell functions including proliferation, gene expression, cell cycle, differentiation, ...
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ژورنال
عنوان ژورنال: Nature Reviews Drug Discovery
سال: 2012
ISSN: 1474-1776,1474-1784
DOI: 10.1038/nrd3871